Risperdal :: Drugs Schizophrenia Essays

Risperdal Risperidone is an atypical antipsychotic used to alleviate the symptoms of schizophrenia. Schizophrenia is defined by its effects in altering perception, thoughts, or consciousness called hallucinations or delusions. It affects about 1% of the population, with about 2 million people affected in the United States. About 50% of those affected become severely and permanently disabled and dependent upon public assistance. Schizophrenics make up about 10% of the totally disabled population and as much as 14% of the homeless. The United States spends about $70 billion annually. About 1 out of 4 patients will attempt suicide, and 1 in 10 will succeed. There is great social stigma associated with the disease (Sarason & Sarason, 2001, pg. 350). The dopamine theory behind the cause of schizophrenia states that in part excess dopamine is a possible factor or there is more than an average number of dopamine, Type 2 receptors. Risperidone acts on the dopamine D2 receptor (Sarason, et al, 2001, pg. 368). Risperidone is a psychotropic drug and is part of the chemical class of benzisoxazole derivatives used as a treatment for schizophrenia, with some results for bipolar manic disorder, as well. The molecular formula is C23H27FN4O2, with a molecular weight of 410.49 (Ereshefsky & Mascarena, 2003). Route of administration is oral. Once the drug passes the esophagus and stomach, it makes its way into the small intestines. There are beds of capillaries within the intestine walls.